SCHEMBL30600414

SCHEMBL30600414

Cc1ccc(C(=O)NCc2ccc3nnn(C4CCC(=O)NC4=O)c(=O)c3c2)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 14/20 0.48
DDB1 Q16531 10/20 0.48
GSPT1 P15170 7/20 0.48
IKZF3 Q9UKT9 1/20 0.48
ENPP2 Q13822 1/20 0.38
KDM4E B2RXH2 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21751073 1.00 CRBN (0.48) CRBNDDB1GSPT1IKZF3ENPP2
SCHEMBL21768342 0.94 CRBN (0.51) CRBNDDB1GSPT1IKZF3KDM4E
SCHEMBL21751065 0.88 CRBN (0.62) CRBNDDB1GSPT1IKZF3
SCHEMBL30600416 0.87 CRBN (0.47) CRBNDDB1GSPT1
SCHEMBL28357790 0.87 CRBN (0.47) CRBNDDB1GSPT1
SCHEMBL21751108 0.82 CRBN (0.62) CRBNDDB1GSPT1IKZF3
SCHEMBL30600394 0.82 CRBN (0.62) CRBNDDB1GSPT1IKZF3
SCHEMBL31305213 0.81 CRBN (0.51) CRBNDDB1GSPT1IKZF3
SCHEMBL4098722 0.80 DDB1 (0.55) CRBNDDB1GSPT1IKZF3ENPP2
SCHEMBL21751092 0.78 CRBN (0.58) CRBNDDB1GSPT1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621664-B Novel piperidine-2, 6-dione derivatives and uses thereof 韩国化学研究院 2023-08-01 CN disclosed