Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132132 | 0.88 | CYP3A4 (0.48) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL30170447 | 0.88 | CYP3A4 (0.48) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL7569519 | 0.88 | CYP3A4 (0.48) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL28408368 | 0.88 | HPRT1 (0.64) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL17477396 | 0.85 | TDP1 (0.41) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL29440576 | 0.84 | CYP3A4 (0.48) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL133687 | 0.84 | CYP3A4 (0.48) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL28908055 | 0.80 | TDP1 (0.44) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL18788590 | 0.79 | TDP1 (0.44) | HPRT1ALDH1A1TDP1HSD17B10CYP2A6 | |
| SCHEMBL15661190 | 0.78 | CYP2A6 (0.41) | ALDH1A1TDP1CYP2A6TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050469-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2024-02-15 | — | — | US | claimed |
| US-11779598-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (US) | 2023-10-10 | — | — | US | claimed |
| US-20220047628-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2022-02-17 | — | — | US | claimed |
| US-10828327-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-11-10 | — | — | US | claimed |
| US-20200061110-A1 | SYNTHESIS AND ANTIMICROBIAL USES OF DINUCLEAR SILVER(I) PYRAZOLATES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-02-27 | — | — | US | claimed |
| US-20240050469-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2024-02-15 | — | — | US | disclosed |
| US-11779598-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220047628-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2022-02-17 | — | — | US | disclosed |
| US-11160829-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200376025-A1 | SYNTHESIS AND ANTIMICROBIAL USES OF DINUCLEAR SILVER(I) PYRAZOLATES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-12-03 | — | — | US | disclosed |
| US-10828327-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-11-10 | — | — | US | disclosed |
| US-20200061110-A1 | SYNTHESIS AND ANTIMICROBIAL USES OF DINUCLEAR SILVER(I) PYRAZOLATES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828327-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-11160829-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-20220047628-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-20240050469-A1 | Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-20200376025-A1 | SYNTHESIS AND ANTIMICROBIAL USES OF DINUCLEAR SILVER(I) PYRAZOLATES | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-20200061110-A1 | SYNTHESIS AND ANTIMICROBIAL USES OF DINUCLEAR SILVER(I) PYRAZOLATES | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
| US-11779598-B2 | Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates | POLR1C, ZC3HAV1, HELZ | HPRT1 2524/4885ALDH1A1 3502/4885TDP1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.