Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12481659 | 0.86 | MEN1 (0.61) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL12486513 | 0.77 | MEN1 (0.79) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL12485614 | 0.75 | MEN1 (0.87) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL10187337 | 0.75 | MEN1 (0.81) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL12487662 | 0.75 | MEN1 (0.74) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL1097149 | 0.74 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL856014 | 0.74 | MEN1 (0.78) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL12484521 | 0.73 | MEN1 (0.70) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL12485502 | 0.73 | MEN1 (0.70) | MEN1KMT2ARAB9ANPC1CDK4 | |
| SCHEMBL374352 | 0.73 | LCK (0.66) | MEN1KMT2ARAB9ANPC1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | claimed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | claimed |
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | disclosed |