SCHEMBL2175224

SCHEMBL2175224

C=Cc1cc(C=CC(=O)O)ccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 3/20 0.50
MAPK1 P28482 3/20 0.50
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA3 P07451 3/20 0.50
CA4 P22748 3/20 0.50
CA6 P23280 3/20 0.50
CA5A P35218 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
AKR1B10 O60218 3/20 0.50
AKR1B1 P15121 3/20 0.50
HPGD P15428 2/20 0.50
DPP4 P27487 2/20 0.50
THRB P10828 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13661074 0.81 KDM4E (0.47) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL111230 0.80 KDM4E (0.58) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL584596 0.80 KDM4E (0.58) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL5859847 0.77 AKR1C3 (0.64) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL1199056 0.77 TTR (0.47) KDM4EALDH1A1HPGDTTRALOX5
SCHEMBL5859843 0.77 AKR1C3 (0.64) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL14472602 0.77 KDM4E (0.70) KDM4EALDH1A1HSD17B10MAPK1CA12
Urea SCHEMBL11181323 0.77 TDP1 (0.38) KDM4EALDH1A1HPGDHDAC3HDAC1
SCHEMBL926134 0.76 AKR1C3 (0.54) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL926135 0.76 AKR1C3 (0.54) KDM4EALDH1A1HSD17B10MAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048778-B1 Fibrous materials with a fire resistant coating CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-06-21 EP claimed
US-6617382-B1 Comprises melamine polyphosphate as flame retardant; useful in drapes, carpets, automobile seat covers, railroad seat covers, and covers for childrens' beds. CLARIANT GMBH (DE) 2003-09-09 US claimed
US-6613435-B1 Bio-supportive matrices, methods of making and using the same LURITEK, INC. 2003-09-02 US claimed
US-5629259-A CREDIT CARDS, IDENTIFICATION AND TELEPHONE CARDS, IMPROVED IMAGE RESOLUTION, SUBLIMINATION IMAGE TRANSFERRING DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1997-05-13 US claimed
EP-0527303-B1 Insulation-forming material for fire protection DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-08-23 EP claimed
EP-0514484-B1 THERMALLY ASSISTED PROCESS FOR TRANSFERRING SMALL ELECTROSTATOGRAPHIC TONER PARTICLES TO A THERMOPLASTIC BEARING RECEIVER EASTMAN KODAK CO (US) 1994-05-04 EP claimed
EP-0381297-B1 Heat transfer sheet DAINIPPON PRINTING CO LTD (JP) 1993-12-22 EP claimed
EP-0381297-A1 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
US-4766053-A PERMANENT SUPPORT AND IMAGE TRANSFERABLE SHEET FUJI PHOTO FILM CO., LTD. (JP) 1988-08-23 US claimed
US-4732815-A MULTILAYER, HOT MELTS, INKS DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1988-03-22 US claimed
EP-0173532-A2 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1986-03-05 EP claimed
WO-1984000568-A1 A COLOURING COMPOSITION EPPING RUBBER (AU) 1984-02-16 WO claimed
CN-103513528-A Compounds and methods of forming compounds useful as toner DOW GLOBAL TECHNOLOGIES LLC 2014-01-15 CN disclosed
EP-2031450-B1 Electrophotographic image- receiving sheet and image forming method using the same FUJIFILM CORP (JP) 2012-05-16 EP disclosed
CN-101135866-B Electrophotographic image-receiving sheet, method for producing the same and image forming method FUJI PHOTO FILM CO LTD 2011-11-23 CN disclosed
US-7972759-B2 Electrophotographic image-receiving sheet, method for producing the same and image forming method FUJIFILM CORPORATION (JP) 2011-07-05 US disclosed
US-4221839-A POLYMER BINDER COATINGS, ORGANOMETALLIC TOXICANT M&T CHEMICALS INC. (US) 1980-09-09 US disclosed
US-4157974-A PIGMENT, COPOLYMER OF STYRENE OR VINYLTOLUENE AND AN ACRYLIC ESTER IN AN ALIPHATIC HYDROCARBON; DISPERSING, GRINDING, COOLING HOECHST AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4032338-A HOLOGRAPHIC RECORDING MEDIUM EMPLOYING A PHOTOCONDUCTIVE LAYER AND A LOW MOLECULAR WEIGHT MICROCRYSTALLINE POLYMERIC LAYER RCA CORPORATION (US) 1977-06-28 US disclosed
US-4012253-A Holographic recording medium RCA CORPORATION (US) 1977-03-15 US disclosed