SCHEMBL584596

SCHEMBL584596

Cc1ccc(C=CC(=O)O)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.58
ALDH1A1 P00352 5/20 0.58
HSD17B10 Q99714 3/20 0.58
MAPK1 P28482 3/20 0.58
CA12 O43570 3/20 0.58
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA3 P07451 3/20 0.58
CA4 P22748 3/20 0.58
CA6 P23280 3/20 0.58
CA5A P35218 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
CA5B Q9Y2D0 3/20 0.58
POLB P06746 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
HPGD P15428 2/20 0.58
AKR1B10 O60218 2/20 0.58
AKR1B1 P15121 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111230 1.00 KDM4E (0.58) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL27875555 0.85 HSD17B10 (0.56) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL5859843 0.85 AKR1C3 (0.64) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL14472602 0.85 KDM4E (0.70) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL471934 0.85 KDM4E (0.70) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL471935 0.85 KDM4E (0.70) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL5859847 0.85 AKR1C3 (0.64) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL14926717 0.84 IAPP (0.61) KDM4EALDH1A1POLBTDP1LMNA
SCHEMBL7003926 0.83 KDM4E (0.53) KDM4EALDH1A1HSD17B10MAPK1CA12
SCHEMBL7003924 0.83 KDM4E (0.53) KDM4EALDH1A1HSD17B10MAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268614-B1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO KK (JP) 2013-05-15 EP claimed
US-8258340-B2 Method for producing β-mercapto carboxylic acids SHOWA DENKO K.K. (JP) 2012-09-04 US claimed
EP-2205557-B1 METHOD FOR PRODUCING BETA-MERCAPTOCARBOXYLIC ACIDS SHOWA DENKO KK (JP) 2012-02-29 EP claimed
US-20110015436-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO K.K. (JP) 2011-01-20 US claimed
US-20110004017-A1 METHOD FOR PRODUCING B-MERCAPTOCARBOXYLIC ACIDS SHOWA DENKO K.K. (JP) 2011-01-06 US claimed
EP-2268614-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS Showa Denko K.K. (JP) 2011-01-05 EP claimed
WO-2009113711-A1 METHOD FOR PRODUCING -MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO K.K. (JP) 2009-09-17 WO claimed
US-3943137-A ANTITUMOR UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) 1976-03-09 US claimed
JP-4149165-A None JP disclosed
CN-120577461-A Honey variety identification method based on amino acid and polyphenol compounds and application thereof 甘肃省食品检验研究院(甘肃省动物源性食品基因检测中心) 2025-09-02 CN disclosed
CN-114105702-A Compound liquid fertilizer 河北省农林科学院农业资源环境研究所 2022-03-01 CN disclosed
US-9802898-B2 Phenyl and tertbutylacetic acid substituted pyridinones having anti-HIV effects VIIV HEALTHCARE UK LIMITED (GB) 2017-10-31 US disclosed
US-20170217890-A1 PHENYL AND TERTBUTYLACETIC ACID SUBSTITUTED PYRIDINONES HAVING ANTI-HIV EFFECTS VIIV HEALTHCARE UK LIMITED (GB) 2017-08-03 US disclosed
EP-3172189-A1 PHENYL AND TERTBUTYLACETIC ACID SUBSTITUTED PYRIDINONES HAVING ANTI-HIV EFFECTS VIIV Healthcare UK Limited (GB) 2017-05-31 EP disclosed
JP-H04149165-A PRODUCTION OF AMINO BENZOIC ACID DERIVATIVE MARUKO SEIYAKU KK 1992-05-22 JP disclosed
US-RE32944-E Aromatic carboxylic amide derivatives Kissei Yakuhin Kogyo Kabushiki (JP) 1989-06-06 US disclosed
US-4070484-A Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same KISSEI PHARMACEUTICAL CO., LTD. (JA) 1978-01-24 US disclosed
US-4026896-A ANTIALLERGENS KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) 1977-05-31 US disclosed
US-3943137-A ANTITUMOR UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) 1976-03-09 US disclosed
US-3940422-A ANTIALLERGEN KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217890-A1 PHENYL AND TERTBUTYLACETIC ACID SUBSTITUTED PYRIDINONES HAVING ANTI-HIV EFFECTS TERT, CD4, TYMP KDM4E 1927/4885ALDH1A1 271/4885HSD17B10 1073/4885
US-20110015436-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS CBS, ALDH7A1, CBR1 KDM4E 3784/4885ALDH1A1 8/4885HSD17B10 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.