SCHEMBL2175226

SCHEMBL2175226

C=Cc1cccc(C)c1C=CC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 6/20 0.45
PTGER2 P43116 6/20 0.45
PTGER4 P35408 5/20 0.45
PTGER1 P34995 4/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
NFKB1 P19838 1/20 0.43
CA4 P22748 1/20 0.43
KDM4E B2RXH2 2/20 0.40
HDAC3 O15379 1/20 0.40
TNKS O95271 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059378 0.84 HCAR2 (0.50) PTGER3PTGER2PTGER4PTGER1CA1
SCHEMBL2059374 0.84 HCAR2 (0.50) PTGER3PTGER2PTGER4PTGER1CA1
Bicarbonate SCHEMBL10781692 0.82 ALDH1A1 (0.38) PTGER3PTGER2PTGER4PTGER1CA1
SCHEMBL2819645 0.81 CA1 (0.52) PTGER3PTGER2PTGER4PTGER1CA1
SCHEMBL4630499 0.79 CA1 (0.39) PTGER3PTGER2PTGER4PTGER1CA1
Benzene SCHEMBL28149237 0.78 ALDH1A1 (0.38) CA1CA2KDM4EALDH1A1MAPT
SCHEMBL11834874 0.77 CA1 (0.52) PTGER3PTGER2PTGER4PTGER1CA1
SCHEMBL27700509 0.77 CXCR5 (0.37) CA1CA2KDM4EALDH1A1
SCHEMBL20169602 0.77 CXCR5 (0.37) CA1CA2KDM4EALDH1A1
SCHEMBL3645893 0.76 MAOB (0.45) PTGER3PTGER2PTGER4PTGER1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048778-B1 Fibrous materials with a fire resistant coating CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-06-21 EP claimed
US-6617382-B1 Comprises melamine polyphosphate as flame retardant; useful in drapes, carpets, automobile seat covers, railroad seat covers, and covers for childrens' beds. CLARIANT GMBH (DE) 2003-09-09 US claimed
US-6613435-B1 Bio-supportive matrices, methods of making and using the same LURITEK, INC. 2003-09-02 US claimed
US-5629259-A CREDIT CARDS, IDENTIFICATION AND TELEPHONE CARDS, IMPROVED IMAGE RESOLUTION, SUBLIMINATION IMAGE TRANSFERRING DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1997-05-13 US claimed
EP-0527303-B1 Insulation-forming material for fire protection DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-08-23 EP claimed
EP-0514484-B1 THERMALLY ASSISTED PROCESS FOR TRANSFERRING SMALL ELECTROSTATOGRAPHIC TONER PARTICLES TO A THERMOPLASTIC BEARING RECEIVER EASTMAN KODAK CO (US) 1994-05-04 EP claimed
EP-0381297-B1 Heat transfer sheet DAINIPPON PRINTING CO LTD (JP) 1993-12-22 EP claimed
EP-0381297-A1 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
US-4766053-A PERMANENT SUPPORT AND IMAGE TRANSFERABLE SHEET FUJI PHOTO FILM CO., LTD. (JP) 1988-08-23 US claimed
US-4732815-A MULTILAYER, HOT MELTS, INKS DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1988-03-22 US claimed
EP-0173532-A2 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1986-03-05 EP claimed
WO-1984000568-A1 A COLOURING COMPOSITION EPPING RUBBER (AU) 1984-02-16 WO claimed
CN-103513528-A Compounds and methods of forming compounds useful as toner DOW GLOBAL TECHNOLOGIES LLC 2014-01-15 CN disclosed
EP-2031450-B1 Electrophotographic image- receiving sheet and image forming method using the same FUJIFILM CORP (JP) 2012-05-16 EP disclosed
CN-101135866-B Electrophotographic image-receiving sheet, method for producing the same and image forming method FUJI PHOTO FILM CO LTD 2011-11-23 CN disclosed
US-7972759-B2 Electrophotographic image-receiving sheet, method for producing the same and image forming method FUJIFILM CORPORATION (JP) 2011-07-05 US disclosed
US-4221839-A POLYMER BINDER COATINGS, ORGANOMETALLIC TOXICANT M&T CHEMICALS INC. (US) 1980-09-09 US disclosed
US-4157974-A PIGMENT, COPOLYMER OF STYRENE OR VINYLTOLUENE AND AN ACRYLIC ESTER IN AN ALIPHATIC HYDROCARBON; DISPERSING, GRINDING, COOLING HOECHST AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4032338-A HOLOGRAPHIC RECORDING MEDIUM EMPLOYING A PHOTOCONDUCTIVE LAYER AND A LOW MOLECULAR WEIGHT MICROCRYSTALLINE POLYMERIC LAYER RCA CORPORATION (US) 1977-06-28 US disclosed
US-4012253-A Holographic recording medium RCA CORPORATION (US) 1977-03-15 US disclosed