Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059374 | 0.88 | HCAR2 (0.50) | CA1CA2CA4NFKB1ATM | |
| SCHEMBL2059378 | 0.88 | HCAR2 (0.50) | CA1CA2CA4NFKB1ATM | |
| SCHEMBL942824 | 0.86 | CA1 (0.61) | CA1CA2CA4NFKB1HDAC3 | |
| SCHEMBL942822 | 0.86 | CA1 (0.61) | CA1CA2CA4NFKB1HDAC3 | |
| SCHEMBL25119539 | 0.81 | TRPA1 (0.42) | CA1CA2CA4NFKB1TRPA1 | |
| SCHEMBL3645893 | 0.80 | MAOB (0.45) | CA1CA2CA4NFKB1PTGER1 | |
| SCHEMBL3645896 | 0.80 | MAOB (0.45) | CA1CA2CA4NFKB1PTGER1 | |
| SCHEMBL11321981 | 0.80 | ALDH1A1 (0.50) | CA1CA2CA4NFKB1ATM | |
| SCHEMBL4543959 | 0.79 | NFKB1 (0.69) | CA1CA2CA4NFKB1PTGER1 | |
| SCHEMBL3423203 | 0.79 | NFKB1 (0.69) | CA1CA2CA4NFKB1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |