SCHEMBL21752934

SCHEMBL21752934

O=Cc1ccc(Oc2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.48
PARP10 Q53GL7 1/20 0.45
PARP3 Q9Y6F1 1/20 0.45
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
RAB9A P51151 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
GPR35 Q9HC97 1/20 0.44
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 2/20 0.42
CASP1 P29466 2/20 0.42
CYP2A6 P11509 1/20 0.41
KCNH2 Q12809 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
MAPT P10636 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547869 0.89 HTT (0.44) HAO1MEN1NPC1POLBRAB9A
SCHEMBL10740141 0.89 HTT (0.44) HAO1MEN1NPC1POLBRAB9A
SCHEMBL11678689 0.89 HTT (0.44) HAO1MEN1NPC1POLBRAB9A
SCHEMBL3438249 0.87 HDAC1 (0.46) HAO1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL6704196 0.85 HAO1 (0.59) HAO1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL3243130 0.85 ESR2 (0.46) ALDH1A1KDM4ESMN1; SMN2LMNACYP2A6
SCHEMBL4052078 0.82 HRH3 (0.57) MEN1NPC1POLBRAB9ABLM
SCHEMBL4058957 0.82 HRH3 (0.57) MEN1NPC1POLBRAB9ABLM
SCHEMBL11997230 0.80 HRH3 (0.55) MEN1NPC1POLBRAB9ABLM
SCHEMBL4048737 0.80 HRH3 (0.55) MEN1NPC1POLBRAB9ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368595-A1 NOVEL MOLECULES Xeniopro GmbH (DE) 2025-12-04 US disclosed
CN-119954697-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2025-05-09 CN disclosed
CN-119930483-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2025-05-06 CN disclosed
CN-118290322-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2024-07-05 CN disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US disclosed
US-20220354949-A1 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2022-11-10 US disclosed
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2022-08-11 US disclosed
EP-3840834-A2 AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS Xeniopro GmbH (DE) 2021-06-30 EP disclosed
EP-3841091-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY Xeniopro GmbH (DE) 2021-06-30 EP disclosed
CN-112930337-A Antiproliferative phenoxy (hetero) aryl ethers 赛尼欧普罗有限责任公司 2021-06-08 CN disclosed
CN-112888479-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2021-06-01 CN disclosed
WO-2020039088-A2 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2020-02-27 WO disclosed
WO-2020039094-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY Xeniopro GmbH (DE) 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220354949-A1 NOVEL COMPOUNDS MUSK, TYR, IKZF3 HAO1 2538/4885PARP10 1501/4885PARP3 2650/4885
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR HAO1 739/4885PARP10 2271/4885PARP3 2019/4885
US-20250368595-A1 NOVEL MOLECULES MUSK, IKZF3, TYR HAO1 2858/4885PARP10 1273/4885PARP3 2581/4885
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR HAO1 739/4885PARP10 2271/4885PARP3 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.