Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052078 | 1.00 | HRH3 (0.57) | HRH3RAB9ANPC1MEN1POLB | |
| SCHEMBL11997230 | 0.99 | HRH3 (0.55) | HRH3RAB9ANPC1MEN1POLB | |
| SCHEMBL4048737 | 0.99 | HRH3 (0.55) | HRH3RAB9ANPC1MEN1POLB | |
| SCHEMBL4054763 | 0.86 | HRH3 (0.49) | HRH3RAB9ANPC1MEN1POLB | |
| SCHEMBL4060325 | 0.83 | RAB9A (0.50) | HRH3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22139428 | 0.82 | HRH3 (0.62) | HRH3KCNH2MRGPRX4LMNA | |
| SCHEMBL21752934 | 0.82 | HAO1 (0.48) | HRH3RAB9ANPC1MEN1POLB | |
| SCHEMBL4050773 | 0.81 | RAB9A (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23223734 | 0.81 | RAB9A (0.69) | RAB9ANPC1MEN1KMT2APTPN1 | |
| SCHEMBL11614936 | 0.81 | RAB9A (0.69) | RAB9ANPC1MEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |