Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MDH1 | P40925 | 1/20 | 0.31 |
| ▸ | MDH2 | P40926 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21752971 | 0.84 | MEN1 (0.40) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21752970 | 0.82 | CASP2 (0.40) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21769895 | 0.79 | LMNA (0.35) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21753065 | 0.77 | LMNA (0.35) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21769975 | 0.77 | CASP2 (0.36) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21769893 | 0.75 | LMNA (0.33) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21769894 | 0.73 | MEN1 (0.31) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21752924 | 0.73 | MEN1 (0.44) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21752969 | 0.72 | MEN1 (0.40) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL27845478 | 0.70 | LMNA (0.61) | LMNAMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3840834-A2 | AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS | Xeniopro GmbH (DE) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020039088-A2 | NOVEL COMPOUNDS | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |