Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 8/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753329 | 0.83 | ACACA (0.53) | ACACAITGB3ITGA2BKCNJ1ACACB | |
| SCHEMBL16430910 | 0.80 | ACACA (0.48) | ACACAITGB3ITGA2BKCNJ1ACACB | |
| SCHEMBL21753321 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BCYP2D6MEN1CYP1A2 | |
| SCHEMBL21753334 | 0.78 | OPRL1 (0.58) | ACACAITGB3ITGA2BCYP2D6 | |
| SCHEMBL6620291 | 0.77 | SSTR5 (0.49) | — | |
| SCHEMBL485114 | 0.76 | AR (0.47) | ITGB3ITGA2BCYP2D6MEN1CYP1A2 | |
| SCHEMBL17444273 | 0.74 | OPRL1 (0.66) | KCNJ1 | |
| SCHEMBL17444275 | 0.74 | OPRL1 (0.66) | KCNJ1 | |
| SCHEMBL16637299 | 0.73 | POLB (0.45) | ACACAKCNJ1CYP2D6TSHRPOLB | |
| SCHEMBL29550707 | 0.71 | TSHR (0.42) | CYP2D6MEN1CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039029-A1 | SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |