Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA4 | P22748 | 6/20 | 0.38 |
| ▸ | CA5A | P35218 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454848 | 0.86 | TSHR (0.52) | TSHRLMNAKMT2AALDH1A1CA12 | |
| SCHEMBL2454844 | 0.86 | TSHR (0.52) | TSHRLMNAKMT2AALDH1A1CA12 | |
| SCHEMBL14278404 | 0.86 | TSHR (0.52) | TSHRLMNAKMT2AALDH1A1CA12 | |
| SCHEMBL7025660 | 0.85 | TSHR (0.51) | TSHRLMNAKMT2APTPN1ALDH1A1 | |
| SCHEMBL6303221 | 0.85 | TSHR (0.71) | TSHRLMNAKMT2APTPN1GALR3 | |
| SCHEMBL9393500 | 0.84 | TSHR (0.50) | TSHRLMNAKMT2AALDH1A1MMP12 | |
| SCHEMBL18343982 | 0.84 | TSHR (0.50) | TSHRLMNAKMT2AALDH1A1MMP12 | |
| SCHEMBL14740699 | 0.83 | TSHR (0.49) | TSHRLMNAKMT2APTPN1ALDH1A1 | |
| SCHEMBL6297105 | 0.82 | TSHR (0.48) | TSHRLMNAKMT2APTPN1ALDH1A1 | |
| SCHEMBL20095195 | 0.81 | TSHR (0.59) | TSHRLMNAKMT2APTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038377-A1 | NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, AND USE THEREOF | 苏州瑞博生物技术有限公司 | 2020-02-27 | — | — | WO | disclosed |