Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | PDIA4 | P13667 | 2/20 | 0.41 |
| ▸ | PDIA3 | P30101 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454848 | 1.00 | TSHR (0.52) | TSHRLMNAKMT2ACYP2D6THRB | |
| SCHEMBL14278404 | 1.00 | TSHR (0.52) | TSHRLMNAKMT2ACYP2D6THRB | |
| SCHEMBL18343982 | 0.93 | TSHR (0.50) | TSHRLMNAKMT2ACYP2D6THRB | |
| SCHEMBL9393500 | 0.93 | TSHR (0.50) | TSHRLMNAKMT2ACYP2D6THRB | |
| SCHEMBL23778463 | 0.91 | TSHR (0.44) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL9798062 | 0.90 | LMNA (0.48) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL9798051 | 0.90 | LMNA (0.48) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL20095195 | 0.90 | TSHR (0.59) | TSHRLMNAKMT2ACYP2D6THRB | |
| SCHEMBL21753464 | 0.86 | TSHR (0.51) | TSHRLMNAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL7025660 | 0.86 | TSHR (0.51) | TSHRLMNAKMT2AALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331550-B1 | SHORT SYNTHETIC PATHWAY FOR 1,6:2,3-DIANHYDRO-BETA-D-MANNOPYRANOSE | SANOFI SA (FR) | 2013-11-13 | — | — | EP | disclosed |
| US-8461359-B2 | Short synthetic pathway for 1,6:2,3-dianhydro-β-D-mannopyranose | SANOFI (FR) | 2013-06-11 | — | — | US | disclosed |
| US-20110224446-A1 | SHORT SYNTHETIC PATHWAY FOR 1,6:2,3-DIANHYDRO-BETA-D-MANNOPYRANOSE | SANOFI-AVENTIS (FR) | 2011-09-15 | — | — | US | disclosed |
| US-6106872-A | HYDROLYSIS OF GLYCOSIDES TO FORM MONOGLYCOSIDES AND ENZYME HYDROLYSIS | GIST-BROCADES NV (NL) | 2000-08-22 | — | — | US | disclosed |
| US-5985618-A | ENZYMATICALLY HYDROLYZING | CIST-BROCADES, N.V. (NL) | 1999-11-16 | — | — | US | disclosed |
| EP-0416713-B2 | Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained | DSM NV (NL) | 1999-06-23 | — | — | EP | disclosed |
| US-5573926-A | HYDROLYSIS | GIST-BROCADES, N.V. (NL) | 1996-11-12 | — | — | US | disclosed |
| EP-0332281-B1 | PROCESS FOR OBTAINING AROMA COMPONENTS AND AROMAS FROM THEIR PRECURSORS OF A GLYCOSIDIC NATURE | GIST-BROCADES N.V. (NL) | 1992-09-23 | — | — | EP | disclosed |
| US-5023330-A | Starch pyrolysis, distillation, filtration, chromatography separation using ion exchange resin | SUEDZUCKER-AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| EP-0416713-A1 | Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained | GIST-BROCADES N.V. (NL) | 1991-03-13 | — | — | EP | disclosed |
| EP-0332281-A1 | Process for obtaining aroma components and aromas from their precursors of a glycosidic nature | GIST-BROCADES N.V. (NL) | 1989-09-13 | — | — | EP | disclosed |
| EP-0327920-A2 | Method for the preparation of 1,6-beta-D-anhydroglucopyranose (levoglucosan) with a high purity | SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) | 1989-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224446-A1 | SHORT SYNTHETIC PATHWAY FOR 1,6:2,3-DIANHYDRO-BETA-D-MANNOPYRANOSE | MANBA, ALG1, MAN2A1 | TSHR 3777/4885LMNA 3265/4885KMT2A 2629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.