Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102896 | 0.92 | CA2 (0.44) | KMT2ASIGMAR1ADRB2KCNH2GRM5 | |
| SCHEMBL21752922 | 0.89 | ATM (0.46) | KMT2AGPR183GRM5CYP2C9CYP2C19 | |
| SCHEMBL21753810 | 0.88 | ATM (0.47) | KMT2AGRM5 | |
| SCHEMBL16099279 | 0.86 | CA2 (0.43) | KMT2ASIGMAR1ADRB2KCNH2GRM5 | |
| SCHEMBL21756473 | 0.86 | ALDH1A1 (0.46) | KMT2AGRM5NPC1 | |
| SCHEMBL21753815 | 0.85 | GRM5 (0.49) | KMT2AGRM5 | |
| SCHEMBL21753812 | 0.85 | ALDH1A1 (0.46) | KMT2AGPR183GRM5NPC1 | |
| SCHEMBL21753809 | 0.85 | SMN1; SMN2 (0.45) | KMT2AGPR183GRM5CYP1A2CYP3A4 | |
| SCHEMBL16099458 | 0.84 | PANK3 (0.44) | GRM5 | |
| SCHEMBL21753823 | 0.84 | MAPT (0.46) | FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040326-A1 | PHENYLACETIC ACID DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 가천대학교 산학협력단 | 2020-02-27 | — | — | WO | claimed |