Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753809 | 0.97 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMEN1KMT2ARXRA | |
| SCHEMBL21753823 | 0.92 | MAPT (0.46) | SMN1; SMN2KDM4EHRH3ALDH1A1GRM5 | |
| SCHEMBL21753808 | 0.90 | GRM5 (0.47) | ALOX5RXRARXRBRXRGGRM5 | |
| SCHEMBL21753814 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMEN1KMT2ARXRA | |
| SCHEMBL21753807 | 0.89 | NR1H4 (0.50) | ALOX5PTGS1RXRARXRBRXRG | |
| SCHEMBL21753813 | 0.87 | ALOX5 (0.44) | ALOX5RXRARXRBRXRGHRH3 | |
| SCHEMBL21756473 | 0.87 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1GRM5GAA | |
| SCHEMBL21753815 | 0.86 | GRM5 (0.49) | MEN1KMT2AGRM5 | |
| SCHEMBL21752922 | 0.86 | ATM (0.46) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL21753812 | 0.86 | ALDH1A1 (0.46) | SMN1; SMN2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040326-A1 | PHENYLACETIC ACID DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | 가천대학교 산학협력단 | 2020-02-27 | — | — | WO | disclosed |