Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25473507 | 0.90 | HDAC3 (0.56) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25064819 | 0.90 | HDAC3 (0.56) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25473525 | 0.88 | HDAC3 (0.57) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25064730 | 0.79 | ENPP2 (0.64) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25474220 | 0.79 | ENPP2 (0.51) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL20715704 | 0.78 | SMN1; SMN2 (0.50) | TRPV1MEN1POLBCYP2C9TSHR | |
| SCHEMBL22593897 | 0.77 | MAPT (0.47) | TRPV1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25064833 | 0.76 | NPC1 (0.58) | POLBHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL25474710 | 0.76 | MAPT (0.45) | TRPV1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL10345260 | 0.76 | HDAC3 (0.69) | MEN1POLBKMT2AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570192-B2 | Anti-wall teichoic antibodies and conjugates | GENENTECH, INC. (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570192-B2 | Anti-wall teichoic antibodies and conjugates | STT3A, STT3B, DDOST | TRPV1 4441/4885MEN1 3388/4885CYP1A2 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.