⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321983 | 0.67 | — | — | |
| Urea SCHEMBL29068779 | 0.67 | — | — | |
| Urea SCHEMBL27259265 | 0.67 | — | — | |
| Urea SCHEMBL1592955 | 0.64 | — | — | |
| Acetamide SCHEMBL20411647 | 0.64 | — | — | |
| Urea SCHEMBL1705605 | 0.64 | — | — | |
| Acetamide SCHEMBL2232674 | 0.64 | — | — | |
| Acetamide SCHEMBL3337894 | 0.64 | LMNA (1.00) | — | |
| Acetamide SCHEMBL20411642 | 0.64 | — | — | |
| Urea SCHEMBL9555545 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568867-B2 | Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis | GALAPAGOS NV (BE) | 2020-02-25 | — | — | US | disclosed |