Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ANTXR2 | P58335 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756831 | 0.88 | ANTXR2 (0.42) | KMT2AMEN1ANTXR2LMNAGAPDH | |
| SCHEMBL15481901 | 0.88 | ANTXR2 (0.42) | KMT2AMEN1ANTXR2LMNAGAPDH | |
| SCHEMBL16803259 | 0.87 | KMT2A (0.42) | KMT2AMEN1ANTXR2LMNAGAPDH | |
| SCHEMBL16756713 | 0.87 | ANTXR2 (0.45) | KMT2AMEN1ANTXR2LMNAGAPDH | |
| SCHEMBL15481823 | 0.87 | ANTXR2 (0.45) | KMT2AMEN1ANTXR2LMNAGAPDH | |
| SCHEMBL21754796 | 0.81 | UPP1 (0.48) | KMT2AMEN1GAPDHCYP2C9CYP2C19 | |
| SCHEMBL21754828 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1SMN1; SMN2MAPTPTPN1 | |
| SCHEMBL15481925 | 0.79 | KMT2A (0.44) | KMT2AMEN1ANTXR2LMNASMN1; SMN2 | |
| SCHEMBL21754766 | 0.78 | KMT2A (0.41) | KMT2AMEN1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL15481835 | 0.74 | KMT2A (0.40) | KMT2AMEN1LMNASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570112-B2 | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same | FUJIFILM CORPORATION (JP) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570112-B2 | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same | TYMS, TYMP, RRM2B | KMT2A 1034/4885MEN1 2277/4885ANTXR2 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.