SCHEMBL21756050

SCHEMBL21756050

Cc1cc(Cl)ccc1-c1cccc(B(O)O)c1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.37
NOTUM Q6P988 2/20 0.36
ENPP2 Q13822 1/20 0.36
ESR2 Q92731 1/20 0.36
CRHR1 P34998 2/20 0.35
SCN5A Q14524 1/20 0.34
SCN9A Q15858 1/20 0.34
HSD11B1 P28845 1/20 0.34
TSHR P16473 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CNR1 P21554 1/20 0.33
S100A4 P26447 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
MAP2 P11137 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3106465 0.85 GRM2 (0.43) GRM2NOTUMENPP2CRHR1HSD11B1
SCHEMBL29719717 0.74 NOTUM (0.53) GRM2NOTUMHSD11B1S100A4
SCHEMBL30145623 0.74 ENPP2 (0.50) GRM2NOTUMENPP2HSD11B1S100A4
SCHEMBL4221663 0.74 KMT2A (0.45) GRM2NOTUMESR2TSHRCNR1
SCHEMBL30984364 0.73 NPC1 (0.49) GRM2NOTUMCRHR1TSHRCNR1
SCHEMBL13176936 0.73 NPC1 (0.49) GRM2NOTUMCRHR1TSHRCNR1
SCHEMBL4225660 0.72 GABRA1 (0.64) ALOX5PTGS1PTGS2ALDH1A1SUCNR1
SCHEMBL3106470 0.71 MAP2 (0.43) ENPP2TSHRCNR1S100A4ALDH1A1
SCHEMBL29825793 0.70 CYP3A4 (0.43) ENPP2TSHRALDH1A1
SCHEMBL624402 0.70 CYP3A4 (0.43) ENPP2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed