Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104506 | 0.83 | IDO1 (0.36) | SLC6A4SLC6A2 | |
| SCHEMBL22765684 | 0.79 | KDM4E (0.49) | SLC6A4HTR2AKCNH2KDM4EALDH1A1 | |
| SCHEMBL31378001 | 0.76 | SLC6A4 (0.36) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL8145201 | 0.76 | SLC6A4 (0.56) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL16831106 | 0.75 | SLC6A4 (0.42) | SLC6A4SLC6A2 | |
| SCHEMBL24422626 | 0.74 | KDM4E (0.38) | SLC6A4HTR2AKCNH2KDM4EALDH1A1 | |
| SCHEMBL18619507 | 0.73 | TNIK (0.38) | SLC6A4KCNH2KDM4EALDH1A1SLC6A2 | |
| SCHEMBL28543732 | 0.73 | IDO1 (0.35) | SLC6A4SLC6A2 | |
| SCHEMBL13761530 | 0.73 | APP (0.35) | SLC6A4SLC6A2 | |
| SCHEMBL21756948 | 0.73 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| US-9403829-B2 | Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1H)-one, a solid form thereof and methods of their use | SIGNAL PHARMACEUTICALS, LLC (US) | 2016-08-02 | — | — | US | disclosed |