Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104506 | 0.89 | IDO1 (0.36) | IDO1SLC6A4SLC6A2DHFRGRIN2D | |
| SCHEMBL28480935 | 0.78 | TAAR1 (0.42) | DHFR | |
| SCHEMBL16831106 | 0.77 | SLC6A4 (0.42) | IDO1SLC6A4SLC6A2 | |
| SCHEMBL28538413 | 0.75 | IDO1 (0.38) | IDO1SLC6A4SLC6A2 | |
| SCHEMBL2478774 | 0.74 | POLB (0.47) | IDO1SLC6A4SLC6A2 | |
| SCHEMBL14066702 | 0.73 | ALOX15 (0.38) | SLC6A4SLC6A2 | |
| SCHEMBL21756928 | 0.73 | SLC6A4 (0.39) | SLC6A4SLC6A2 | |
| SCHEMBL8645452 | 0.73 | GABRA1 (0.32) | IDO1SLC6A4SLC6A2GRIN2DGRIN3B | |
| SCHEMBL13019662 | 0.73 | TTR (0.36) | IDO1SLC6A4SLC6A2 | |
| SCHEMBL17745114 | 0.72 | GABRA1 (0.46) | IDO1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232330-B | Method for synthesizing benzene sulfonamide compound from benzene sulfonyl chloride compound and triethylamine through metal-free catalysis | 中国人民解放军国防科技大学 | 2021-03-26 | — | — | CN | disclosed |