Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26137532 | 0.84 | KCNH2 (0.59) | MAPTMEN1KMT2ACYP2A13KCNH2 | |
| SCHEMBL21765349 | 0.79 | HSD17B10 (0.51) | MAPTKMT2ACYP2A13HSD17B10CYP2C9 | |
| SCHEMBL4111089 | 0.78 | CYP2A13 (0.63) | MAPTMEN1KMT2ACYP2A13KCNH2 | |
| SCHEMBL1438683 | 0.77 | CYP2A13 (0.66) | CYP2A13HSD17B10CYP2C9ALOX15HIF1A | |
| SCHEMBL14200319 | 0.75 | KCNH2 (0.59) | MAPTMEN1KMT2ACYP2A13KCNH2 | |
| SCHEMBL21756936 | 0.74 | CYP2A13 (0.47) | MAPTMEN1KMT2ACYP2A13KCNH2 | |
| SCHEMBL1613567 | 0.74 | CYP2C9 (0.53) | MAPTMEN1KMT2ACYP2A13HSD17B10 | |
| SCHEMBL15546497 | 0.74 | CYP2A13 (0.61) | MAPTKMT2ACYP2A13HSD17B10CYP2C9 | |
| SCHEMBL26505561 | 0.73 | MAPT (0.51) | MAPTMEN1KMT2ACYP2A13KCNH2 | |
| SCHEMBL11161472 | 0.72 | MAPT (0.57) | MAPTMEN1KMT2ACYP2A13KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020039088-A2 | NOVEL COMPOUNDS | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |