Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292617 | 0.81 | ESR1 (0.40) | APPMAPTRAPGEF4SLC6A2SLC6A4 | |
| SCHEMBL29768251 | 0.81 | ESR1 (0.40) | APPMAPTRAPGEF4SLC6A2SLC6A4 | |
| SCHEMBL18055972 | 0.79 | APP (0.31) | APP | |
| SCHEMBL3185975 | 0.75 | TDP1 (0.44) | ALDH1A1TSHRALOX15HSD17B10LMNA | |
| SCHEMBL29968345 | 0.74 | APP (0.38) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Bromide SCHEMBL3977210 | 0.73 | TDP1 (0.42) | ALDH1A1TSHRALOX15HSD17B10LMNA | |
| SCHEMBL516025 | 0.73 | ALDH1A1 (0.48) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL2868438 | 0.73 | TDP1 (0.42) | ALDH1A1TSHRALOX15HSD17B10LMNA | |
| SCHEMBL20119975 | 0.71 | KMT2A (0.52) | ALDH1A1TSHRMAPTRAPGEF4 | |
| SCHEMBL21279637 | 0.71 | HSD17B1 (0.40) | APPALDH1A1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |