SCHEMBL21757253

SCHEMBL21757253

CC1(C)OB(c2ccc3cc(-c4nc5ccccc5c5c4ccc4ccccc45)ccc3c2)OC1(C)C

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 8/20 0.53
LPL P06858 7/20 0.53
SNCA P37840 1/20 0.36
DGAT1 O75907 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
HSP90AA1 P07900 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
GRK6 P43250 1/20 0.33
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
DHODH Q02127 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17035106 0.91 LIPG (0.51) LIPGLPLSNCADGAT1KDM4E
SCHEMBL17035107 0.90 LIPG (0.42) LIPGLPLIRAK4KDM4ELMNA
SCHEMBL20352908 0.86 LIPG (0.52) LIPGLPLSNCADGAT1IRAK4
SCHEMBL21537706 0.86 LIPG (0.45) LIPGLPLSNCADGAT1IRAK4
SCHEMBL20967839 0.85 LPL (0.47) LIPGLPLSNCAIRAK4PRMT5
SCHEMBL21537855 0.85 LPL (0.44) LIPGLPLSNCADGAT1IRAK4
SCHEMBL17035146 0.84 LIPG (0.44) LIPGLPLKDM4ELMNAMAPT
SCHEMBL20352794 0.82 LIPG (0.42) LIPGLPLSNCADGAT1IRAK4
SCHEMBL22606546 0.82 LIPG (0.47) LIPGLPLSNCADGAT1KDM4E
SCHEMBL18200529 0.81 LPL (0.38) LIPGLPLDGAT1IRAK4PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11302873-B2 Organic light-emitting device LT MATERIALS CO, LTD. (KR) 2022-04-12 US disclosed
US-20200066996-A1 ORGANIC LIGHT-EMITTING DEVICE HEESUNG MATERIAL LTD. (KR) 2020-02-27 US disclosed