Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078604 | 0.78 | SLC6A2 (0.38) | SSTR4SLC6A2 | |
| SCHEMBL8916691 | 0.78 | SLC6A2 (0.38) | SSTR4SLC6A2 | |
| SCHEMBL15496986 | 0.75 | SLC6A2 (0.39) | SSTR4SLC6A2 | |
| SCHEMBL19370313 | 0.75 | SLC6A2 (0.39) | SSTR4SLC6A2 | |
| SCHEMBL15499257 | 0.75 | SLC6A2 (0.39) | SSTR4SLC6A2 | |
| SCHEMBL26316830 | 0.75 | SLC6A2 (0.36) | SSTR4SLC6A2 | |
| SCHEMBL24897462 | 0.74 | SSTR4 (0.31) | SSTR4 | |
| SCHEMBL5981607 | 0.74 | SLC6A2 (0.41) | SSTR4SLC6A2 | |
| SCHEMBL6142277 | 0.72 | SLC6A2 (0.35) | SLC6A2 | |
| SCHEMBL22081057 | 0.71 | SLC6A2 (0.36) | SSTR4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062803-A1 | AZAINDOLINE COMPOUNDS AS GRANZYME B INHIBITORS | VIDA THERAPEUTICS INC. (CA) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062803-A1 | AZAINDOLINE COMPOUNDS AS GRANZYME B INHIBITORS | GZMB, DNASE1L3, DNASE1 | SSTR4 3653/4885SLC6A2 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.