Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413681 | 0.84 | SHBG (0.39) | SHBGALOX15ALOX12PTPN1ESR1 | |
| SCHEMBL24698730 | 0.84 | SHBG (0.39) | SHBGALOX15ALOX12PTPN1ESR1 | |
| SCHEMBL16736925 | 0.83 | MCL1 (0.47) | SHBGALOX15ALOX12PTPN1ESR1 | |
| SCHEMBL14924927 | 0.82 | SHBG (0.42) | SHBGPKMESR1ESR2KDM4E | |
| SCHEMBL6828121 | 0.82 | SHBG (0.38) | SHBGALOX15ALOX12ESR1ESR2 | |
| SCHEMBL17930510 | 0.81 | SHBG (0.34) | SHBGPTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL5075167 | 0.79 | SHBG (0.54) | SHBGKLF10PKMALOX15ALOX12 | |
| SCHEMBL14283762 | 0.79 | KDM4E (0.50) | SHBGKLF10PKMALOX15ALOX12 | |
| SCHEMBL16736683 | 0.79 | HMGCR (0.48) | ALOX15ALOX12PTPN1ESR1ESR2 | |
| SCHEMBL17244912 | 0.77 | SHBG (0.42) | SHBGPKMALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842410-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | Beijing Wholesomeyird Sci & Tech Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038464-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | 北京厚燊药德科技有限责任公司 | 2020-02-27 | — | — | WO | disclosed |