Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958466 | 0.88 | SHBG (0.39) | SHBGALOX15ALOX12MEN1KMT2A | |
| SCHEMBL31413681 | 0.88 | SHBG (0.39) | SHBGALOX15ALOX12HPGDPDE4A | |
| SCHEMBL24698730 | 0.88 | SHBG (0.39) | SHBGALOX15ALOX12HPGDPDE4A | |
| SCHEMBL1318936 | 0.86 | SHBG (0.42) | SHBGALOX15ALOX12MEN1KMT2A | |
| SCHEMBL14924927 | 0.86 | SHBG (0.42) | SHBGRAB9AHPGDPDE4APDE4B | |
| SCHEMBL29613199 | 0.86 | SHBG (0.42) | SHBGALOX15RAB9AHPGDPDE4A | |
| SCHEMBL17244912 | 0.86 | SHBG (0.42) | SHBGALOX15RAB9AHPGDPDE4A | |
| SCHEMBL597251 | 0.84 | PTPN1 (0.36) | SHBGALOX15ALOX12PDE4APDE4B | |
| SCHEMBL21757382 | 0.82 | SHBG (0.44) | SHBGALOX15ALOX12HPGDMEN1 | |
| SCHEMBL21362629 | 0.80 | PGK1 (0.36) | SHBGALOX15ALOX12HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |