Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.46 |
| ▸ | ADH1A | P07327 | 4/20 | 0.46 |
| ▸ | ADH1C | P00326 | 3/20 | 0.43 |
| ▸ | ADH7 | P40394 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618357 | 0.76 | ADH1B (0.59) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL17461453 | 0.72 | ADH1B (0.54) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL17729399 | 0.70 | PRMT1 (0.32) | — | |
| SCHEMBL8373078 | 0.70 | — | — | |
| SCHEMBL16404601 | 0.69 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL4912168 | 0.67 | ADH1B (0.59) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19658308 | 0.67 | ADH1B (1.00) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL21997344 | 0.67 | ADH1B (1.00) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL115609 | 0.67 | — | — | |
| SCHEMBL21062003 | 0.67 | RAB9A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215509-B1 | SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |