Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 11/20 | 0.51 |
| ▸ | WNT3A | P56704 | 11/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089515 | 0.82 | CTNNB1 (0.68) | CTNNB1WNT3APTPN1ERCC5FEN1 | |
| SCHEMBL138307 | 0.81 | PTPN1 (0.53) | CTNNB1WNT3APTPN1ERCC5FEN1 | |
| SCHEMBL14732971 | 0.81 | CTNNB1 (0.61) | CTNNB1WNT3APTPN1ERCC5FEN1 | |
| SCHEMBL27257973 | 0.80 | CES2 (0.47) | CES2CES1KMT2AMEN1MAPT | |
| SCHEMBL23982058 | 0.79 | MEN1 (0.41) | CTNNB1WNT3APTPN1ERCC5FEN1 | |
| SCHEMBL26261196 | 0.79 | CTNNB1 (0.51) | CTNNB1WNT3AERCC5FEN1KMT2A | |
| SCHEMBL24069168 | 0.79 | ERCC5 (0.50) | ERCC5FEN1CES2CES1KMT2A | |
| SCHEMBL9178035 | 0.76 | ALDH1A1 (0.47) | CES2CES1KMT2AMEN1MAPT | |
| SCHEMBL8616416 | 0.76 | CTNNB1 (0.56) | CTNNB1WNT3APTPN1ERCC5FEN1 | |
| SCHEMBL3121320 | 0.76 | ALDH1A1 (0.57) | CTNNB1WNT3APTPN1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |