Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759250 | 0.92 | TGFBR1 (0.71) | TGFBR1TGFBR2 | |
| SCHEMBL18041506 | 0.90 | TGFBR1 (0.81) | TGFBR1TGFBR2 | |
| SCHEMBL21759286 | 0.86 | TGFBR1 (0.67) | TGFBR1TGFBR2 | |
| SCHEMBL21759213 | 0.85 | TGFBR1 (0.73) | TGFBR1TGFBR2 | |
| SCHEMBL21759155 | 0.85 | TGFBR1 (0.74) | TGFBR1TGFBR2 | |
| SCHEMBL18041925 | 0.82 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18041910 | 0.81 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL18041565 | 0.80 | TGFBR1 (0.83) | TGFBR1TGFBR2 | |
| SCHEMBL18041663 | 0.79 | TGFBR1 (0.78) | TGFBR1TGFBR2 | |
| SCHEMBL18041836 | 0.79 | TGFBR1 (1.00) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265454-B1 | TGF-BETA INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2020-02-26 | — | — | EP | disclosed |