Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24166176 | 0.92 | HTR2A (0.31) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL205285 | 0.80 | GABRR1 (0.38) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL14295036 | 0.80 | GABRR1 (0.38) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL10313066 | 0.74 | GABRR1 (0.31) | GABRR1GABRR2 | |
| SCHEMBL23655640 | 0.74 | GABRR1 (0.31) | GABRR1GABRR2 | |
| SCHEMBL13037059 | 0.74 | — | — | |
| SCHEMBL3468818 | 0.74 | — | — | |
| SCHEMBL1500329 | 0.74 | — | — | |
| SCHEMBL15107928 | 0.74 | — | — | |
| SCHEMBL15107313 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371203-B1 | BORTEZOMIB CONJUGATES AND METHODS USING SAME | UNIV ROCHESTER (US) | 2020-02-26 | — | — | EP | disclosed |