Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.30 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759159 | 0.92 | HTR2A (0.31) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL205285 | 0.84 | GABRR1 (0.38) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL14295036 | 0.84 | GABRR1 (0.38) | HTR2AHTR2CHTR2BGABRR1GABRR2 | |
| SCHEMBL10313066 | 0.77 | GABRR1 (0.31) | GABRR1GABRR2 | |
| SCHEMBL22403731 | 0.77 | — | — | |
| SCHEMBL23487145 | 0.75 | — | — | |
| SCHEMBL23746623 | 0.75 | — | — | |
| SCHEMBL12510525 | 0.75 | GBA1 (0.35) | — | |
| SCHEMBL331684 | 0.74 | — | — | |
| SCHEMBL23655640 | 0.72 | GABRR1 (0.31) | GABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002033-A1 | BINDING PROTEIN HAVING H2L2 AND HCAB STRUCTURES | 和铂医药(上海)有限责任公司 | 2022-01-06 | — | — | WO | disclosed |