Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313066 | 0.95 | GABRR1 (0.31) | GABRR1GABRR2 | |
| SCHEMBL3405444 | 0.80 | — | — | |
| SCHEMBL22241265 | 0.80 | — | — | |
| SCHEMBL13178820 | 0.80 | — | — | |
| SCHEMBL205285 | 0.80 | GABRR1 (0.38) | GABRR1GABRR2 | |
| SCHEMBL14295036 | 0.80 | GABRR1 (0.38) | GABRR1GABRR2 | |
| SCHEMBL15502042 | 0.74 | NOS3 (0.32) | GABRR1GABRR2 | |
| SCHEMBL21759159 | 0.74 | HTR2A (0.31) | GABRR1GABRR2 | |
| SCHEMBL24166176 | 0.72 | HTR2A (0.31) | GABRR1GABRR2 | |
| SCHEMBL24170389 | 0.70 | GABRR1 (0.32) | GABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413895-B1 | C5-C6-OXACYLIC FUSED IMINOTHIADIAZINE DIOXIDE COMPOUNDS BEARING AN ETHER LINKER AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME (US) | 2021-07-21 | — | — | EP | disclosed |