Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759112 | 0.85 | TGFBR1 (0.73) | TGFBR1TGFBR2 | |
| SCHEMBL21759155 | 0.85 | TGFBR1 (0.74) | TGFBR1TGFBR2 | |
| SCHEMBL21759286 | 0.84 | TGFBR1 (0.67) | TGFBR1TGFBR2 | |
| SCHEMBL18057167 | 0.84 | TGFBR1 (0.77) | TGFBR1TGFBR2 | |
| SCHEMBL18042084 | 0.84 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL21748160 | 0.83 | TGFBR1 (0.82) | TGFBR1TGFBR2 | |
| SCHEMBL21759212 | 0.82 | TGFBR1 (0.74) | TGFBR1TGFBR2 | |
| SCHEMBL21759138 | 0.82 | TGFBR1 (0.74) | TGFBR1TGFBR2 | |
| SCHEMBL21759284 | 0.82 | TGFBR1 (0.81) | TGFBR1TGFBR2 | |
| SCHEMBL18042038 | 0.82 | TGFBR1 (1.00) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265454-B1 | TGF-BETA INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2020-02-26 | — | — | EP | disclosed |