Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 1/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199487 | 0.88 | CCND3 (0.69) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL13042221 | 0.84 | MAPT (0.60) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL3966827 | 0.83 | CCND3 (0.67) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL1303899 | 0.82 | CCND3 (0.61) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL250171 | 0.79 | CCND3 (0.70) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL9373255 | 0.79 | CCND3 (0.61) | CCND3CDK6RAB9ANPC1PDE10A | |
| Hydrochloric Acid SCHEMBL7000982 | 0.78 | CCND3 (0.68) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL8350123 | 0.78 | CCND3 (0.60) | CCND3CDK6RAB9ANPC1HPGD | |
| SCHEMBL14804457 | 0.76 | PDE10A (0.72) | PDE10A | |
| SCHEMBL10428595 | 0.74 | PDE10A (0.53) | CCND3CDK6RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585462-B1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICALS CO (JP) | 2020-02-26 | — | — | EP | disclosed |