Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.69 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24637376 | 1.00 | CRBN (0.69) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30569011 | 0.92 | CRBN (0.62) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL21759952 | 0.92 | CRBN (0.71) | CRBN | |
| SCHEMBL29873934 | 0.88 | CRBN (0.62) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL23250036 | 0.88 | CRBN (0.62) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL24046320 | 0.88 | CRBN (0.62) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20129298 | 0.88 | CRBN (0.62) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL23267271 | 0.87 | CRBN (0.64) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL21877059 | 0.87 | CRBN (0.64) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL25756473 | 0.86 | CRBN (0.61) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186069-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-10-05 | — | — | WO | disclosed |