SCHEMBL21760465

SCHEMBL21760465

CC1(C)c2cc(C(=O)O)ccc2-c2ccc(N(c3ccccc3)c3cccc4ccccc34)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.36
HSD17B10 Q99714 1/20 0.36
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 2/20 0.35
PTPN1 P18031 2/20 0.35
TSHR P16473 1/20 0.34
RORC P51449 2/20 0.34
MPL P40238 1/20 0.34
SRD5A2 P31213 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
ALK Q9UM73 1/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
RARG P13631 1/20 0.34
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21760522 0.95 PDK2 (0.39) SIGMAR1HSD17B10RXRARXRBRXRG
SCHEMBL4084514 0.89 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL17693517 0.89 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL29511997 0.89 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL29390340 0.89 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL14073254 0.88 SIGMAR1 (0.38) SIGMAR1MEN1KMT2APDK2
SCHEMBL133504 0.88 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL15495964 0.88 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL12640117 0.88 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2
SCHEMBL15138682 0.88 SIGMAR1 (0.40) SIGMAR1MEN1KMT2APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11637256-B2 Quantum dots with charge-transporting ligands NANOSYS, INC. (US) 2023-04-25 US disclosed
WO-2020040982-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 WO disclosed
US-20200067006-A1 QUANTUM DOTS WITH CHARGE-TRANSPORTING LIGANDS NANOSYS, INC. (US) 2020-02-27 US disclosed