Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390340 | 1.00 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL17693517 | 1.00 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL4084514 | 1.00 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL12640117 | 0.99 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL15138682 | 0.99 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL133504 | 0.99 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL15495964 | 0.99 | SIGMAR1 (0.40) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL12439592 | 0.97 | SIGMAR1 (0.39) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL13907748 | 0.97 | SIGMAR1 (0.39) | SIGMAR1PDK2L3MBTL1DHFRMEN1 | |
| SCHEMBL12439779 | 0.97 | SIGMAR1 (0.39) | SIGMAR1PDK2L3MBTL1DHFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220112996-A1 | JEWELRY AND GEM STONE LIGHTING SYSTEMS AND APPARATUSES AND METHOD MAKING AND USING SAME | ASHLEY PAUL (US) | 2022-04-14 | — | — | US | disclosed |