Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701151 | 0.85 | GAA (0.58) | GAATSHRNPC1MEN1KMT2A | |
| SCHEMBL22588191 | 0.85 | ALDH1A1 (0.62) | GAATSHRNPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28106647 | 0.83 | GAA (0.57) | GAATSHRNPC1MEN1KMT2A | |
| SCHEMBL29145021 | 0.81 | PTGDR2 (0.62) | TSHRMEN1KMT2APKMLMNA | |
| SCHEMBL30514814 | 0.80 | SMN1; SMN2 (0.65) | GAATSHRKMT2AALDH1A1PKM | |
| SCHEMBL1790129 | 0.80 | SMN1; SMN2 (0.65) | GAATSHRKMT2AALDH1A1PKM | |
| SCHEMBL12325555 | 0.79 | KDM4E (0.53) | GAATSHRNPC1MEN1KMT2A | |
| SCHEMBL21760688 | 0.79 | GAA (0.52) | GAATSHRNPC1MEN1KMT2A | |
| SCHEMBL29134872 | 0.76 | PTPN1 (0.54) | GAATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL30016133 | 0.76 | PTPN1 (0.54) | GAATSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |