Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016133 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2PTPN6GAAHSD17B10 | |
| SCHEMBL17363249 | 0.82 | ACLY (0.54) | GAAMEN1KMT2ASLC22A12BRD4 | |
| SCHEMBL15545672 | 0.81 | GAA (0.50) | PTPN1PTPN2PTPN6GAASLC22A12 | |
| SCHEMBL10585599 | 0.79 | HSD17B10 (0.47) | PTPN1PTPN2PTPN6HSD17B10MEN1 | |
| SCHEMBL10585601 | 0.79 | ALDH1A1 (0.51) | PTPN1PTPN2PTPN6GAAHSD17B10 | |
| SCHEMBL15662236 | 0.78 | TSHR (0.56) | PTPN1GAAHSD17B10MEN1KMT2A | |
| SCHEMBL31500466 | 0.77 | SLC22A12 (0.49) | PTPN1PTPN2PTPN6SLC22A12POLB | |
| SCHEMBL26927487 | 0.77 | SLC22A12 (0.49) | PTPN1PTPN2PTPN6SLC22A12POLB | |
| SCHEMBL21760929 | 0.76 | GAA (0.59) | GAAMEN1KMT2APOLBLMNA | |
| SCHEMBL859011 | 0.74 | PIK3CD (0.42) | PTPN1PTPN2PTPN6HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |