Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | ALPL | P05186 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760943 | 1.00 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RALPLL3MBTL1 | |
| SCHEMBL2197205 | 0.91 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RALPL | |
| SCHEMBL2197208 | 0.91 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RALPL | |
| SCHEMBL6102679 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RALPLL3MBTL1 | |
| SCHEMBL17393987 | 0.84 | L3MBTL1 (0.64) | L3MBTL1PIK3C2GDRD2ADRA1DADRA1A | |
| SCHEMBL21760617 | 0.84 | L3MBTL1 (0.64) | L3MBTL1PIK3C2GDRD2ADRA1DADRA1A | |
| SCHEMBL17393986 | 0.84 | L3MBTL1 (0.64) | L3MBTL1PIK3C2GDRD2ADRA1DADRA1A | |
| SCHEMBL3006664 | 0.84 | MCHR1 (0.66) | MCHR1ADRA2ANPY5RALPLL3MBTL1 | |
| SCHEMBL4732954 | 0.83 | ALPL (0.49) | MCHR1ADRA2ANPY5RALPLDRD2 | |
| SCHEMBL1723245 | 0.83 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RALPLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |