Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760973 | 0.84 | SMN1; SMN2 (0.51) | ALPLSMN1; SMN2GAAALDH1A1PKM | |
| SCHEMBL21760975 | 0.84 | KMT2A (0.55) | ALPLSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL21760970 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAALDH1A1KMT2ATSHR | |
| SCHEMBL1404336 | 0.75 | ALPL (1.00) | ALPLGAAALDH1A1MEN1KMT2A | |
| SCHEMBL21761089 | 0.75 | SMN1; SMN2 (0.67) | ALPLSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL21760971 | 0.73 | SMN1; SMN2 (0.48) | ALPLSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL12335431 | 0.72 | NAMPT (0.70) | ALPLMEN1KMT2AL3MBTL1 | |
| SCHEMBL21761090 | 0.70 | SMN1; SMN2 (0.54) | ALPLSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL15211570 | 0.70 | ALPL (0.80) | ALPLGAAALDH1A1MEN1KMT2A | |
| SCHEMBL21177215 | 0.70 | SMN1; SMN2 (0.56) | ALPLSMN1; SMN2GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |
| US-9884826-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2018-02-06 | — | — | US | disclosed |