Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.56 |
| ▸ | DRD3 | P35462 | 12/20 | 0.56 |
| ▸ | DRD1 | P21728 | 8/20 | 0.51 |
| ▸ | DRD5 | P21918 | 7/20 | 0.51 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025183 | 0.90 | DRD2 (0.62) | DRD2DRD3DRD1DRD5PNMT | |
| SCHEMBL8012748 | 0.85 | DRD2 (0.64) | DRD2DRD3PNMTDRD4AKR1C3 | |
| SCHEMBL26161470 | 0.84 | DRD2 (0.59) | DRD2DRD3DRD1DRD5PNMT | |
| SCHEMBL22628948 | 0.83 | DRD2 (0.53) | DRD2DRD3PNMT | |
| SCHEMBL3363261 | 0.80 | PNMT (0.60) | DRD2DRD3PNMTMAOAMAOB | |
| SCHEMBL29618357 | 0.80 | PNMT (0.60) | DRD2DRD3PNMTMAOAMAOB | |
| SCHEMBL8222195 | 0.80 | PNMT (0.60) | DRD2DRD3PNMTMAOAMAOB | |
| SCHEMBL29741121 | 0.80 | PNMT (0.60) | DRD2DRD3PNMTMAOAMAOB | |
| SCHEMBL26160315 | 0.80 | DRD2 (0.49) | DRD2DRD3PNMTAKR1C3AKR1C1 | |
| Hydrochloric Acid SCHEMBL15205820 | 0.79 | PNMT (0.58) | DRD2DRD3PNMTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039028-A1 | TETRAHYDRO-BENZOAZEPINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |