Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763388 | 0.91 | ALOX5 (0.40) | ALOX5AHRMEN1KMT2AMAPT | |
| SCHEMBL23676613 | 0.84 | ALOX5 (0.36) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL15306316 | 0.83 | ALOX5 (0.41) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL15178580 | 0.83 | ALOX5 (0.41) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL23676615 | 0.81 | ALOX5 (0.43) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL14295291 | 0.81 | ALOX5 (0.40) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL20651500 | 0.81 | ALDH1A1 (0.38) | AHRKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22059188 | 0.80 | ALOX5 (0.39) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL20650381 | 0.80 | ALOX5 (0.39) | ALOX5AHRKDM4EMEN1KMT2A | |
| SCHEMBL15747049 | 0.80 | TOP2A (0.44) | ALOX5AHRKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |