Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 2/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133620 | 0.89 | CCR3 (0.61) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL28540968 | 0.85 | CCR3 (0.46) | TACR3CCR3CARM1PRMT6PRMT3 | |
| SCHEMBL18786497 | 0.83 | CCR3 (0.53) | TACR3CCR3CARM1PRMT6PRMT3 | |
| SCHEMBL29138824 | 0.82 | SLC6A2 (0.48) | CCR3 | |
| SCHEMBL31307968 | 0.82 | SLC6A2 (0.48) | CCR3 | |
| SCHEMBL29138831 | 0.82 | SLC6A2 (0.48) | CCR3 | |
| SCHEMBL18970534 | 0.78 | ATM (0.47) | TACR3ALDH1A1 | |
| SCHEMBL22470627 | 0.78 | CCR3 (0.45) | CCR3 | |
| SCHEMBL6970404 | 0.78 | CCR3 (0.45) | CCR3 | |
| SCHEMBL3436965 | 0.77 | PRMT6 (0.62) | TACR3CCR3CARM1PRMT6PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| EP-2496230-B1 | IRE-1 ALPHA INHIBITORS | FOSUN ORINOVE PHARMATECH INC (CN) | 2020-02-26 | — | — | EP | disclosed |