Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946531 | 1.00 | ERN1 (0.61) | ERN1 | |
| SCHEMBL13639937 | 0.78 | ERN1 (0.76) | ERN1 | |
| SCHEMBL21763673 | 0.78 | ERN1 (0.70) | ERN1 | |
| SCHEMBL21763550 | 0.78 | ERN1 (0.70) | ERN1 | |
| SCHEMBL4487723 | 0.78 | ERN1 (0.50) | ERN1 | |
| SCHEMBL12277536 | 0.77 | PGR (0.54) | ERN1 | |
| SCHEMBL2762231 | 0.76 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12767134 | 0.76 | ERN1 (1.00) | ERN1 | |
| SCHEMBL21763593 | 0.76 | ERN1 (0.61) | ERN1 | |
| SCHEMBL12767176 | 0.75 | ERN1 (1.00) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496230-B1 | IRE-1 ALPHA INHIBITORS | FOSUN ORINOVE PHARMATECH INC (CN) | 2020-02-26 | — | — | EP | disclosed |