Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763550 | 0.86 | ERN1 (0.70) | ERN1 | |
| SCHEMBL12767176 | 0.83 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12675796 | 0.81 | ERN1 (0.74) | ERN1 | |
| SCHEMBL12675803 | 0.81 | ERN1 (0.74) | ERN1 | |
| SCHEMBL12767154 | 0.81 | ERN1 (1.00) | ERN1 | |
| SCHEMBL18717305 | 0.80 | ERN1 (0.70) | ERN1 | |
| SCHEMBL21763340 | 0.78 | ERN1 (0.61) | ERN1 | |
| SCHEMBL29946531 | 0.78 | ERN1 (0.61) | ERN1 | |
| SCHEMBL21763675 | 0.77 | ERN1 (0.60) | ERN1 | |
| SCHEMBL12277731 | 0.77 | PGR (0.57) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496230-B1 | IRE-1 ALPHA INHIBITORS | FOSUN ORINOVE PHARMATECH INC (CN) | 2020-02-26 | — | — | EP | disclosed |