Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21763375 | 0.95 | PDK2 (0.36) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL12703011 | 0.91 | PDK2 (0.38) | PDK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21787751 | 0.88 | PDK2 (0.39) | PDK2SLC6A2SLC6A4 | |
| SCHEMBL17886997 | 0.88 | PDK2 (0.39) | PDK2SLC6A2SLC6A4 | |
| SCHEMBL24686801 | 0.87 | LPL (0.40) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL20466609 | 0.87 | LPL (0.40) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL10034405 | 0.87 | LPL (0.40) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL10034344 | 0.86 | LPL (0.39) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL24686798 | 0.86 | LPL (0.39) | LPLLIPGESR1ESR2CA1 | |
| SCHEMBL13367454 | 0.86 | PDK2 (0.46) | LPLLIPGESR1ESR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |