Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 16/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886997 | 1.00 | PDK2 (0.39) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21787832 | 0.93 | PDK2 (0.37) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21416352 | 0.92 | PDK2 (0.43) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21973024 | 0.91 | PDK2 (0.42) | PDK2 | |
| SCHEMBL12703005 | 0.91 | PDK2 (0.43) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21763021 | 0.88 | PDK2 (0.38) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL21763429 | 0.88 | LPL (0.38) | PDK2SLC6A2SLC6A4 | |
| SCHEMBL21763285 | 0.87 | PDK2 (0.40) | PDK2MAPTL3MBTL1 | |
| SCHEMBL21763424 | 0.87 | PDK2 (0.37) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL24177613 | 0.87 | PDK2 (0.38) | PDK2MLNRNR1I2CHRM2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2022-01-06 | — | — | US | disclosed |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | NR0B2, KCNJ2, TRRAP | PDK2 1160/4885MLNR 2934/4885NR1I2 287/4885 |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | KCNJ2, KCNA2, CYP2J2 | PDK2 1400/4885MLNR 3829/4885NR1I2 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.