Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576802 | 0.81 | PRKCI (0.41) | PRKCIKIF11CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL24514642 | 0.75 | PIK3CA (0.35) | CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL17742693 | 0.73 | FYN (0.56) | PRKCIKIF11CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL31532683 | 0.73 | FYN (0.56) | PRKCIKIF11CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL23921308 | 0.70 | CYP17A1 (0.38) | CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23712244 | 0.70 | CYP17A1 (0.38) | CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22306711 | 0.70 | PRKCI (0.42) | PRKCIKIF11CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL27623946 | 0.69 | MEN1 (0.55) | PRKCIKIF11NOTUMAURKAKMO | |
| SCHEMBL16108896 | 0.68 | KMO (0.56) | PRKCICYP3A4NOTUMAURKAKMO | |
| SCHEMBL29627221 | 0.67 | KMO (0.71) | PRKCINOTUMAURKAKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369737-B1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | SAMSUNG ELECTRONICS CO LTD (KR) | 2020-02-26 | — | — | EP | disclosed |